MT2 10 mg (Mélanotan 2)

MT2 10 mg (Melanotan 2) is a synthetic cyclic analog of alpha-MSH (melanotropic hormone), a non-selective agonist of melanocortin receptors. Its cyclic structure gives it greater stability and potency than the natural hormone, making MT2 one of the most studied peptides in research on melanogenesis, photoprotection, and appetite regulation.

Molecular mechanism of action:

(1) MC1R receptor agonism: stimulates melanocytes and melanin (eumelanin) synthesis, inducing skin pigmentation.

(2) MC4R receptor agonism modulates central circuits of appetite and sexual function.

(3) MC3R receptor agonism: involved in energy homeostasis and inflammation.

(4) Photoprotection: the increase in melanin strengthens the body’s natural defenses against UV rays.

(5) Structural stability: cyclization prolongs the half-life compared to endogenous α-MSH.

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• Melanogenesis and skin pigmentation
• Photoprotection and response to UV
• Appetite regulation and energy homeostasis (MC4R pathway)
• Research on sexual function
• Study of melanocortin receptors
• Melanocortinic anti-inflammatory pathways

Analytical data

• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂ | Molecular weight: 1024.2 DaHPLC Purity: ≥ 99% (certified by Janoshik, certificate of analysis available per batch)
• Appearance: White, sterile, freeze-dried powder
• Solubility: Bacteriostatic water, sterile water, physiological saline solution
• Storage of freeze-dried powder: Up to 24 months at -20°C
• Storage after reconstitution: 4 weeks at +4 °C, protected from light.
• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂
• Molecular weight: 1024.2 Da
• HPLC Purity: ≥ 99% (certified by Janoshik, certificate of analysis available per batch)
• Appearance: White, sterile, freeze-dried powder
• Solubility: bacteriostatic water, sterile water, physiological saline solution
• Storage of freeze-dried powder: Up to 24 months at -20°C
• Storage after reconstitution: 4 weeks at +4 °C, protected from light.

Reconstitution and storage: Reconstitute with sterile or bacteriostatic water (recommended concentration: 2 to 5 mg/mL). The reconstituted solution is stable for 4 weeks at +4°C, protected from light. Unreconstituted lyophilized powder can be stored for up to 24 months at -20°C. Avoid repeated freeze-thaw cycles and prolonged contact with air after reconstitution.